Department of Experimental Medicine II
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  portrait of the institute
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Tumour Suppressor APC

Amer Family of Proteins

Conductin in Cancer

Activin B and renal cell carcinoma


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The Nikolaus-Fiebiger-Center

The Nikolaus-Fiebiger-Center (NFZ) of Molecular Medicine is a research institution of the Medical Faculty at the Friedrich Alexander University FAU) of Erlangen-Nuernberg. The center harbours two divisions of Experimental Medicine I and II (Connective Tissue Research and Molecular Tumor Research, respectively), a division of Molecular Immunology, a division of Genetics (Science Faculty) as well as several junior research groups of the Interdisciplinary Clinical Research Center (IZKF) of the Medical Faculty. The intention of the research center is to strengthen biomedical research in the Medical School by stimulating cooperations between basic and clinical researchers and giving young clinicians the opportunity to carry out competitive biomedical research projects under the infrastructure of a modern research center.


 
 


The Nikolaus-Fiebiger-Center is well equipped with modern research facilities required for cell and molecular biological research and offers a variety of biochemical, immunological and cell biological seminars, guest lectures and common graduate student seminars. Communication between all scientific and technical staff is greatly facilitated by a modern computer network allowing access to data banks and electronic libraries from each desk. Central equipment such as DNA-sequencing, fluorescence activated cell sorting, confocal laser microscopy, surface plasmon resonance as well as animal facilities are accessible for all scientists and technical personell.




The Department of Experimental Medicine II
 

The department was established in September 2000 with the appointment of Dr. Jürgen Behrens as Professor of Experimental Medicine II. Dr Behrens moved from the Max-Delbrück-Center (MDC) in Berlin where he had been head of an independant research group. Meanwhile the group has expanded considerably, now consisting of 19 people in total.


 
Research interests

 
Our group analyses molecular mechanisms that control tumor development and progression. We are particularly interested in the regulation of the oncogenic wnt signal transduction pathway and in the role of cadherin cell adhesion molecules in epithelial differentiation and metastasis. We also analyse mechanisms of metastasis formation on the level of the tumor cell - endothelial cell interaction and have established DNA microarray technology for large scale gene expression analysis of tumor tissues.
 


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